The Senegalese Football Federation (FSF) smacked the ban on the forward after statements he made in the media about bribery in African football.
An FSF statement read: "Diouf is banned from performing any football-associated activity for the time of five years."
Diouf responded angrily to the FSF's says that he had failed to come out for a disciplinary hearing last week.
The committee desired to ask the Blackburn striker about comments he had made on Radio France International, alleging that "the entire network of African football is corrupt".
He then told French magazine Stade he would "go to fight" with the FSF if they took additional action.
It remains possible, according to the FSF, that the choice could be inverted if Diouf were to appear before the disciplinary committee.
The news approaches as Diouf's club career hangs in the balance.
He has been fined by Blackburn for not succeeding to report on time for pre-season guiding, and was left out for their pre-season tour to Hong Kong .
Manager Steve Kean said in an interview this week that he considered it was time for Diouf to go away from the club, marking that investigations have been made by other clubs.
